Document Type : Original Article


1 Department of Orthodontics and Dentofacial Orthopaedics, Saraswati Dental College, Lucknow

2 Faculty of Dentistry, Dr. Ram Manohar Lohia Institute of Medical Sciences, Lucknow


Introduction – The objective of the authors was to compare the tooth movement using platelet rich plasma (PRP) and conventional method in patients with moderate crowding during leveling and aligning phase.

Methods –Fifty patients were chosen who had moderate crowding in the maxillary arch. Split mouth study design was planned with one quadrant allotted as experimental group (PRP side) and other as control group. 5 injection sites were pre-defined – distal surface of the root of the central incisor, mesial and distal root surfaces of lateral incisor and canine. After the extraction of permanent maxillary first premolars, PRP was injected at the various sites on the experimental side while the other side served as control group. In each group, 4 time points were studied – 0(T0), 21(T1), 42(T2) and 63(T3) days. Tooth movement was measured using Digital Vernier Calliper and statistical analysis was done using paired-t test.

Results – Significant (p<0.001) amount of tooth movement was seen at 21 days. No significant difference in the amount of tooth movement was found at 42 days (p=0.265) and 63 days (p=0.104).

Conclusion – Platelet-Rich Plasma is responsible for accelerating the orthodontic tooth movement in moderate crowding patient when injected during the leveling and aligning phase for the first 21 days after injection while its was non-effective after 42 and 63 days.


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