Document Type : Original Article


1 Post Graduate Student, Department of Orthodontics and Dentofacial Orthopedics, The Oxford Dental College & Hospital, Bangalore, Karnataka, India

2 Professor and Head, Department of Orthodontics and Dentofacial Orthopedics, The Oxford Dental College & Hospital, Bangalore, Karnataka, India

3 Professor, Department of Orthodontics and Dentofacial Orthopedics, The Oxford Dental College & Hospital, Bangalore, Karnataka, India

4 Associate Professor, Department of Orthodontics and Dentofacial Orthopedics, The Oxford Dental College & Hospital, Bangalore, Karnataka, India


Aim: The use of pre-procedural mouth rinse for prevention of COVID-19 can reduce viral load but can alter the bond strength. The purpose of this study was to determine any correlation between the use of these pre-procedural mouth rinse and the shear-bond strength (SBS) of orthodontic brackets.
Methods: Thirty-three maxillary premolars extracted for orthodontic purposes were used. The buccal surfaces of all teeth were bonded with orthodontic brackets. Later, each tooth was embedded into acrylic resin and stored in distilled water. Teeth were randomly divided into three groups (group I: hydrogen peroxide mouth rinse, group II: povidone-iodine mouth rinse, and group III: artificial saliva), and stored in each solution for 12 hours. Later, each tooth was subjected to SBS testing using a universal testing machine. Data were statistically evaluated using one-way analysis of variance (ANOVA) and post hoc test (Tukey’s HSD) with a significance of p< 0.05.
Results: The highest mean SBS was observed in the artificial saliva (control group), followed by the povidone-iodine and hydrogen peroxide groups.
Conclusion: Hydrogen peroxide mouth rinses should not be used during fixed orthodontic treatment because it alters bond strength.


Main Subjects

  1. Singh J, Joshi A, Manjooran T, Raghav S, Gautam A, Patel JH. An in vitro Evaluation of Shear Bond Strength of Orthodontic Brackets after Mouth Rinse. J Contemp Dent Pract. 2018;19(7):862-6. doi: 10.5005/jp-journals-10024 2348. PMID: 30066692.
  2. Phelan AL, Katz R, Gostin LO. The novel coronavirus originating in Wuhan, China: Challenges for Global Health Governance. JAMA. 2020;323(8):709–710. doi: 10.1001/jama.2020.1097. PMID: 31999307.
  3. Ge ZY, Yang, LM, Xia JJ, Fu XH, Zhang YZ. Possible aerosol transmission of COVID-19 and special precautions in dentistry. J Zhejiang Univ Sci B. 2020;21(5):361–368. doi: 10.1631/jzus.B2010010. PMID: 32425001.
  4. Huang N, Pérez P, Kato T, Mikami Y, Okuda K, Gilmore RC, et al. et al. SARS-CoV-2 infection of the oral cavity and saliva. Nat Med.2021;27(5):892–903. doi: 10.1038/s41591-021-01296-8. PMID: 33767405.
  5. Moosavi MS, Aminishakib P, Ansari M. Antiviral mouthwashes: possible benefit for COVID-19 with evidence-based approach. J of oral microbio. 2020;12(1):1794363. doi: 10.1080/20002297.2020. 1794363. PMID: 32944152.
  6. Sette-de-Souza PH, Martins JS, Martins-de-Barros AV, Vieira BR, Costa MF, Araújo FD. A critical appraisal of evidence in the use of preprocedural mouthwash to avoid SARS-CoV-2 transmission during oral interventions. Eur Rev Med Pharmacol Sci. 2020; 24(19):10222-4. doi: 10.26355/eurrev_202010_23245. PMID: 33090432.
  7. Izzetti R, Nisi M, Gabriele M, Graziani F. COVID-19 Transmission in Dental Practice: Brief Review of Preventive Measures in Italy. J of Dent Res. 2020;99(9):1030-38. doi: 10.1177/0022034520920580. PMID: 32302257.
  8. Meng L, Hua F, Bian Z. Coronavirus Disease 2019 (COVID-19): Emerging and Future Challenges for Dental and Oral Medicine. J Dent Res. 2020;99(5):481-487. doi: 10.1177/0022034520914246. PMID: 32162995.
  9. Caruso AA, Del Prete A, Lazzarino AI. Hydrogen peroxide and viral infections: a literature review with research
    hypothesis definition in relation to the current covid-19 pandemic. Med Hypotheses. 2020;144:109910. doi: 10.1016/j.mehy.2020.109910. PMID: 32505069.
  10. Eliades T, Koletsi D. Minimizing the aerosolgenerating procedures in orthodontics in the era of a pandemic: Current evidence on the reduction of hazardous effects for the treatment team and patients. Am J Orthod Dentofacial Orthop. 2020;158(3):330-342. doi: 10.1016/j.ajodo.2020. 06.002. PMID: 32682661.
  11. Demir A, Malkoc S, Sengun A, Koyuturk AE, Sener Y. Effects of Chlorhexidine and Povidone-Iodine Mouth Rinses on the Bond Strength of an Orthodontic Composite. Angle Orthod. 2005;75(3):392–396 doi: 10.1043/0003-3219(2005)75[392:EOCAPM]2.0.CO;2. PMID: 15898378.
  12. Imani MM, Azizi F, Bahrami K, Golshah A, SafariFaramani R. In vitro bleaching effect of hydrogen peroxide with different time of exposition and concentration on shear bond strength of orthodontic brackets to human enamel: A meta-analysis of in vitro studies. Int Orthod. 2020;18(1):22-31. doi: 10.1016/j.ortho.2019.09.001. PMID: 31629708. PMID: 31629708.
  13. Jamilian A, Saghiri MA, Ghasemi M, Ghasemian A, Borna N, Kamali Z. The effects of two mouth rinses on shear bond strength of orthodontic brackets-An Invitro study. Virtual J Orthod. 2011;1:1-7.
  14. Bistey T, Nagy IP, Simo A, Hegedus C. In vitro FT-IR study of the effects of hydrogen peroxide on superficial tooth enamel. J Dent. 2007;35(4):325–30. doi: 10.1016/j.jdent.2006.10.004. PMID: 17116354.