Patients with midline or generalized diastema can be managed successfully by multidisciplinary approach. Our patient was managed by orthodontic, prosthodontic and restorative procedures. After orthodontic treatment, maxillayr labial frenectomy was done for this patient to reduce the possibility of relapse. Restorative treatments were also performed to close the remaining spaces. After all, a fixed prosthodontic bridge was constructed to close the remaining posterior space.