Objectives: White spot lesions( WSLs) are a real problem in patients with fixed orthodontic appliances. This study aimed to evaluate the effects of bioactiveglass toothpaste on remineralization of WSLs around orthodontic brackets.
Methods: A total of 70 extracted premolar were selected and orthodontic brackets were bonded. Artificial caries lesions were created on enamel by immersion for 96 hours in demineralization solution (pH = 4.52) at 37 °C. Occlusal of bracket considered as the treatmet group and gingival of bracket considered as the control group. Specimens were randomly assigned to one of the two groups with sodium fluoride toothpaste applied to group 1, while group 2 received a bioactiveglass toothpaste. The samples were subjected to a 14-day remineralization/demineralzation cycle that consisted of a twice-daily 30-min soak in demineralizing solution (pH=4.52, 37 °C) followed by a five-min toothpaste treatment for occlusal of brackets. The photo of each sample was captured by polarized microscope and the mineralization depth and area were measured by AutoCAD 2007 software. Data were statistically analyzed using independent t-tests and paired t-test by SPSS 23.
Results: The results of this study showed significant differences between treatment group and control group in each of two methods for remineralization area and depth (pvalue<0.001) There were statistically significant difference for treatment group between the two methods for area and depth of remineralization (p-value <0.001).
Conclusion: Both fluoride and bioactiveglass toothpaste were effective for remineralization of WSL and Bioactiveglass toothpaste appears to have a greater effect when compared to that of fluoride toothpaste.