Cleft Lip and Palate
Daniela Garib; Raquel Silva Poletto; Thagid Yasmin Leal Almeida; Silvia Maria Graziadei; Guilherme Janson
Abstract
Aim: This study compared the prevalence of tooth agenesis out of the cleft area in patients with complete bilateral cleft lip and palate (BCLP) with and without agenesis of maxillary permanent lateral incisors.Methods: Tooth agenesis was evaluated in panoramic radiographs taken between 7 and 11 years ...
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Aim: This study compared the prevalence of tooth agenesis out of the cleft area in patients with complete bilateral cleft lip and palate (BCLP) with and without agenesis of maxillary permanent lateral incisors.Methods: Tooth agenesis was evaluated in panoramic radiographs taken between 7 and 11 years of age. Intergroup comparison of tooth agenesis frequency was performed using the chi-square test (P<0.05) and the odds ratio. A sample of 130 patients (87 male, 43 female) with non-syndromic bilateral cleft lip and palate was selected. Group P (n = 44) consisted of individuals with the presence of maxillary lateral incisors on the right and left sides; group UA (n = 40) comprised patients with unilateral agenesis of lateral incisors; group BA (n = 46) comprised patients with bilateral agenesis of lateral incisors. Intergroup comparison for frequency of tooth agenesis outside the cleft area was performed using Chi-square test (p-value <0.05 was considered significant) and the odds ratio (p<0.016).Results: The prevalence of dental agenesis out of the cleft area in groups P, UA, and BA was 31.8%, 32.5%, and 60.8%, respectively. Group BA showed a significantly greater prevalence of tooth agenesis compared with the UA and P groups. There was no significant difference in the odds ratio between any groups. The most common absent teeth were the maxillary second premolars followed by the mandibular second premolars for all groups.Conclusion: Patients with BCLP and bilateral agenesis of maxillary lateral incisors show an increased prevalence of other permanent teeth. This association demonstrates a genetic background of maxillary lateral incisor agenesis at the cleft area.
Cleft Lip and Palate
Arezoo Jahanbin; Farzaneh Lal Alizadeh; Zeinab Ghasemi; Mohammad Reza Fayyazi Bordbar; Reza Shojaeian
Abstract
Objective: This study aimed to compare the quality of life of mothers with children born with cleft lip and palate versus mothers with normal children.Methods & Materials: In this cross-sectional study (descriptive-analytical), 23 mothers of 1 to 3 months old infants with non-syndromic unilateral ...
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Objective: This study aimed to compare the quality of life of mothers with children born with cleft lip and palate versus mothers with normal children.Methods & Materials: In this cross-sectional study (descriptive-analytical), 23 mothers of 1 to 3 months old infants with non-syndromic unilateral cleft lip and palate as well as 23 mothers of normal, non-cleft infants as control group were assessed through the standard quality of life SF-36 questionnaire. Data were collected and analyzed using SPSS software (version 16).Descriptive statistical analysis (mean, percentage, and standard deviation) and analytical statistical test (independent t-test) were used. (P-value <0.05 was considered as significant.)Results: Present study showed the average quality of life score of mothers of infants with non-syndromic unilateral cleft lip and palate was 64.49. Also, the average quality of life score in the control group was 67.06. The mean quality of life of the two groups did not have any statistically significant differences (P =0.597).Also, there was no significant difference between the mothers of affected infants and the control group in eight scopes of the questionnaire including general health, physical function, limitation of role play due to physical reasons, limitation of role play for emotional reasons, social function, physical pain, fatigue or cheerfulness, and mental health (P >0.05). Moreover, both groups had a weak level in terms of role limitation due to physical reasons.Conclusion: According to the results of the present study, both groups did not show a high level of quality of life. Awareness of this issue can guide to providing the necessary social support for all mothers with newborn infants, especially mothers of infants with congenital anomalies such as cleft lip and palate.
Nasrin Farhadian; Zahra Shahrokhi
Abstract
Background and aim: Cleft lip and palate is a common craniofacial congenital malformation. Treatment of this deformity has always been a matter of great concern for physicians and specialists. Data on the incidence and prevalence rate of this condition can help medical authorities plan for the healthcare ...
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Background and aim: Cleft lip and palate is a common craniofacial congenital malformation. Treatment of this deformity has always been a matter of great concern for physicians and specialists. Data on the incidence and prevalence rate of this condition can help medical authorities plan for the healthcare of these patients. Present study aimed to determine the incidence rate and related risk factors of cleft lip and palate in Hamadan province in 2007.
Materials and methods: In this study, 29,822 newborns were evaluated in Hamadan Province hospitals, Iran. Variables such as neonatal gender, parents’ occupations, place of residence, family background, parental consanguinity, and neonatal co-occurring disorders, as well as maternal factors such as age at pregnancy, diseases during pregnancy, medications, drug abuse, smoking, alcohol consumption, radiography, and radiotherapy during pregnancy were recorded. Finally, the data were analyzed using SPSS version 13. Results: 25 neonates (14 male and 11 female subjects) were born with various forms of cleft lip and cleft palate. The incidence rate was 0.83 per 1000 live births. Cleft lip and palate (bi or unilateral) and isolated cleft palate were the most and least frequently reported cases, respectively. In total, 28% of the newborns presented with other co-occurring disorders. Consanguineous marriage was reported in approximately 28% of the neonates’ parents and 12% of the mothers used medications such as phenytoin, imipramine, and trifluoperazine during pregnancy. Conclusion: The incidence rate of cleft lip and palate was close to the average global rate and reports in European and East Asian countries. The incidence rate of clefts was higher in males, compared to females. According to the results, parental consanguinity and mother’s medication, especially at the beginning of pregnancy, are regarded as risk factors for cleft lip and palate.
Mahtab Nouri; Zahra Abdolazimi; Mohammad Reza Badiee
Abstract
Cleft lip and palate is among the most common congenital anomalies of the head and neck region. Treatment of cleft lip and palate is challenging and requires the cooperation of various medical teams. A 15 year-old patient with a cleft lip and palate presented to the Department of Orthodontics at ShahidBeheshti ...
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Cleft lip and palate is among the most common congenital anomalies of the head and neck region. Treatment of cleft lip and palate is challenging and requires the cooperation of various medical teams. A 15 year-old patient with a cleft lip and palate presented to the Department of Orthodontics at ShahidBeheshti University, School of Dentistry complaining of unattractive appearance. The patient had unilateral cleft lip and palate and congenitally missing maxillary left lateral incisor and mentioned a history of surgical repair of the cleft in childhood. He had a concave profile, -5mm overjet, -5mm Wits appraisal and abnormal eruption path of teeth especially for the maxillary left central incisor. The patientunderwent orthodontic treatment without orthognathic surgery. Post-treatment records showed excellent results in terms of occlusion and facial balance and harmony.
