Mohammad Karim Soltani; Amirfarhang Miresmaeili; Bahareh Javanshir; Mojgan AkbarZadeh
Abstract
background and aim: functional appliances with various designs have been introduced in the treatment of Class II malocclusions. The aim of this study was to evaluate dentoskeletal effects of a modified bionator (FA) and Twin Block (TB) functional appliance in treatment of skeletal Class II malocclusion.Method ...
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background and aim: functional appliances with various designs have been introduced in the treatment of Class II malocclusions. The aim of this study was to evaluate dentoskeletal effects of a modified bionator (FA) and Twin Block (TB) functional appliance in treatment of skeletal Class II malocclusion.Method and material: in this retrospective study 30 treated cl II patients with overjet greater than 4mm have been selected from each of two private offices .in each office either FA or TB were used. Pre-treatment and post-treatment lateral cephalograms were digitized and traced with Dolphin Imaging software. ANCOVA and paired T test were used for analysis with SPSS software (19).Results: FA group consisted of 17 girls and 13 boys(mean age: 9.53± 1.1), TB group consisted of 12 boys and 18 girls(mean age: 10.26 ±.944 ) .ANB angle and overjet were reduced significantly in both groups. (p=.000) Mandibular body length demonstrated a significant increase in both groups( 3.06±4.98mm with TB and 3.03±5.52mm with FA ). In Both appliances significant retrusion of upper lip occurred as a result of decrease in overjet (TB=002, FA=.000). No statistical significant difference were found between two appliances.Conclusions: Treatment with both appliances resulted in correction of Class II discrepancy, reduction of overjet, and retrusion of upper lip. No significant dento-skeletal differences were observed between the 2 appliances.
Shahrzad Tamasoki; Amirfarhang Miresmaeili; Masome BasamTabar; S. Fazlollahi; Mojgan Akbarzadeh
Abstract
Background and aim: The etiology of CL/P is thought to be multifactorial with both genetic and environmental factors. Methylentetrahydrofolatereductuse (MTHFR), an important enzyme in folic acid metabolism with C677T polymorphism is one of the most controversial enzyme in CL/P. Our aim was comparison ...
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Background and aim: The etiology of CL/P is thought to be multifactorial with both genetic and environmental factors. Methylentetrahydrofolatereductuse (MTHFR), an important enzyme in folic acid metabolism with C677T polymorphism is one of the most controversial enzyme in CL/P. Our aim was comparison of MTHFR C677T polymorphism in non syndromic CL/P patients with their healthy relatives.Materials and methods: We examined 50 consecutive CL/P patients and 150 their relatives (father, mother and sibling). Blood samples of all cases were collected. DNA extracted using Millers salting out method, and then C677T of MTHFR gene was evaluated by PCR. The results were analysis by Mc-Nemar test with spss19. Results: The frequency of genotype in patients compared with their mother (p= 0.282), father (p= 0.423) and sibling (p=0.607) and we didn’t find significant different between them. Also there was no significant difference between patient’s allele frequency when compared with their mother (p=1.000), father (p=0.405) and sibling (p= 0.804).
Conclusion: In this case-control study, patient’s parents and sibling were used as controls. Frequency of normal allele C677T(C) was higher than altered allele (T) in patients and control groups. We did not find any relation between NSCL/P and C677T polymorphism however; conflicting results have been achieved in different studies.