Massoud Seifi; Roya Hamedi; Maryam Nazirii
Abstract
Background and aim: Orthodontic tooth movement requires remodeling of periodontal tissues, especially alveolar bone. A major objective of investigators is to achieve maximum tooth movement with minimal root damage. The aim of this study is to determine if the rate and amount of orthodontic tooth movement ...
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Background and aim: Orthodontic tooth movement requires remodeling of periodontal tissues, especially alveolar bone. A major objective of investigators is to achieve maximum tooth movement with minimal root damage. The aim of this study is to determine if the rate and amount of orthodontic tooth movement in a sample of rats could be enhanced by the injection of a vitamin D metabolite and Prostaglandin E2.Materials and Methods: Thirty-Two male Wistar rats were randomly divided into 4 groups of eight rats each: 1- 1.5 IU/ml vitamin D was injected into the thigh muscle after installation the orthodontic appliance in first group (Vit D group)
2- 0.1 ml of 1 mg/ml PGE2 was injected submucosally in the second group (PGE2 group).
3- In the third group, 1.5 IU/ml vitamin D and 0.1 ml of 1 mg/ml PGE2 was injected submucosally (Vit D+ PGE2).
4- Distilled water (0.1 ml) was used in control group .In order to calculate the tooth movement; the distance between the upper right first and second molars was measured.Results: All groups have a significant difference with control group (p<0.05). The most mean OTM was observed in the Vit D+PGE2 group (Mean = 0.702± 0.04897mm) that was significantly higher than the Vit D, PGE2 and control groups (P< 0.05). A significant difference (P< 0.05) in root resorption was observed between the PGE2 (0.0192 ±0.000675 mm2) and the other groups.Conclusion: In order to achieve a decrease in root resorption and an increase in OTM, the combination Vit D+PGE2 is useful and there is a synergism effect with Vit D and PGE2.
Massoud Seifi; Majid Bargrizan; Nafiseh Memar-Kermani; Elaheh VAhid-Dastjerdi
Abstract
Aims: Assessment of skeletal and dentoalveolar changes in class II division 1 patients after treatment with Seifi's functional appliance in dental school of Shahid Beheshti. University in 2007-2008. Methods: In this before- after clinical trial study, Seifi's functional appliance was used for ...
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Aims: Assessment of skeletal and dentoalveolar changes in class II division 1 patients after treatment with Seifi's functional appliance in dental school of Shahid Beheshti. University in 2007-2008. Methods: In this before- after clinical trial study, Seifi's functional appliance was used for 15 patients (mean age: 9.84±1.24 year) with class II division I deep bite maloccIusion. All of them had mandibular deficiency and ANB>4 degrees, OJ and OB>4mm. Lateral cephalometric and panoramic radiographs, primary impression via alginate, intraoral and facial photographs were taken at the beginning of the study and after 10.2±2.01 months. The results were compared to each other. The device was two pieces and consisted of an acrylic cap on mandibular incisors and a mid palatal screw and a vertical plate on the upper jaw.Results: In sagittal dimension ANB, 1-SN and OJ decreased and SNB increased (P<0.05). Changes of SNA and IMPA were not significant(P>0.05). In vertical dimension OB decreased and L6-MP increased(P<0.05).Conclusion: Due to simultaneous three dimensional correction in transverse, sagittal and vertical dimensions, the patient benefits of the short period of treatment in the golden growth period. Also correction in skeletal and dentoalveolar relations and improvement in profile happens.
