Orthodontics
Vahid Mollabashi; Maryam Heydarpour; Abbas Farmani; Kimia Saadat; Maryam Farhadian
Abstract
Aim: Formation of white spot lesions (WSL) subsequent to orthodontic treatment is a cosmetic concern. This research assessed the effects of bioactive-glass toothpaste on remineralization of orthodontic white spot lesions.Methods: Orthodontic brackets were boned to seventy extracted premolars. Then they ...
Read More
Aim: Formation of white spot lesions (WSL) subsequent to orthodontic treatment is a cosmetic concern. This research assessed the effects of bioactive-glass toothpaste on remineralization of orthodontic white spot lesions.Methods: Orthodontic brackets were boned to seventy extracted premolars. Then they were submersed in a demineralization solution (pH=4.52) at 37°C for 96 hours, which led to the formation of artificial caries lesions on enamel. Occlusal brackets were assigned to the treatment group, whereas gingival brackets were assigned to the control group.Specimens were allocated to one of two groups: group 1) toothpaste containing sodium fluoride (1,450 ppm), group 2) toothpaste containing bioactive glass (5%). The samples underwent a 14-day remineralization/demineralzation cycle consisting of a twice-daily 30-minute submersion in a demineralizing solution (pH=4.52, 37°C) followed by a five-minute toothpaste treatment for the occlusal of the brackets. Each sample was analyzed using a polarized microscope, and AutoCAD 2007 was used to quantify the mineralization depth and area. Using SPSS version 23, the independent and paired t-tests were used to assess data statistically.Results: In terms of both remineralization area and depth, the study's findings revealed a statistically significant difference between the experimental and control groups (p < 0.001). Area and depth differences between the two remineralization methods in the treatment group were also statistically significant (p < 0.001).Conclusion: Both sodium fluoride and bioactive-glass toothpaste are useful for remineralizing the WSL, while bioactiveglass toothpaste seems to work more effectively than sodium fluoride toothpaste.
Defne Kecik
Abstract
Context: One of the most important aspects of dental profession is to consider the effectiveness of the preventive systems applied and maintain the good oral hygiene, oral health and minimize the risk of caries among the patients. A great spectrum of preventive activities and materials like fluoride ...
Read More
Context: One of the most important aspects of dental profession is to consider the effectiveness of the preventive systems applied and maintain the good oral hygiene, oral health and minimize the risk of caries among the patients. A great spectrum of preventive activities and materials like fluoride applications, fissure sealants; also new technologies like Casein Phosphopeptide-Amorphous calcium phosphate (CCP-ACP) have a wide effect on preventing caries.
Objective: The objective of this systematic review with meta-analysis was to review systematically the clinical trials of CPP-ACP complex and determine the caries preventive effects on the remineralization process.
Data Sources: PubMed, Google Scholar, biomed central, cochrane oral health reviews, Cochrane library, directory of open access journals, Ovid Medline, Web of science and EMBASE were searched up to February 2016. Only articles in English were included. Trials that were considered clinically and methodologically homogeneous and reported on similar outcomes were pooled for meta-analyses. The clinical studies that inspected the effects of casein derivatives in dental practice were included. In vitro studies, case reports, case series, letters to the editors, editorials, review articles and commentaries were not included for the statistical analysis but evaluated to identify the potential outcomes of the further studies.
Study Selection: Of the 3859 studies screened 92 studies were assessed for eligibility, and 22 were selected for inclusion and 11 was in the final sample for meta-analysis. Systematic review was assessed and the remineralization effect of CPP-ACP was demonstrated compared to placebo in the meta-analysis.
Conclusions: The evaluated systematic review with meta-analyses, clinical trials showed the remineralization effect of CPP-ACP on early caries lesions mainly the white spot lesions (WSL’s). In vivo RCT studies reveal a promising caries preventing effect, inducing remineralization and treating dentin hypersensitivity and dry mouth with the use of clinical CPP-ACP application.